Polynucleotides (PN)
Treatment


A refined regenerative treatment to restore skin integrity, luminosity & youthful resilience.

Sadie Aesthetics - Heaton Moor - Polynucleotides (PN) Treatment.jpg

Overview

Polynucleotides are an advanced regenerative treatment formulated with highly purified DNA fragments.

They work in synergy with the skin’s natural biology to support deep hydration, tissue repair and structural renewal.

This treatment is known for its elegant, natural-looking results, making it especially effective for both the under-eye area and full-face rejuvenation.

Clients seeking subtle yet clinically meaningful improvement in skin quality often find PN to be a sophisticated choice.

Polynucleotides (PN)
Benefits

  • Supports long-term tissue regeneration

  • Improves overall skin resilience

  • Enhances hydration and tone

  • Softens fine lines and textural irregularities

  • Particularly effective for delicate under-eye skin

  • Suitable for sensitive and reactive skin types

  • Minimal downtime

Book Your Appointment

for Polynucleotide (PN) Treatment

Single Session

Face
£180

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Course of 4 Treatments

Face
£650
— Save £70

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Single Session

Eyes
£170

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Course of 4 Treatments

Eyes
£580
— Save £100

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How the Treatment Works

  • PN activates fibroblasts — the cells responsible for producing collagen and elastin — supporting a stronger, healthier skin matrix.

  • Polynucleotides attract and retain moisture within the skin, restoring:

    • Softness

    • Elasticity

    • Comfortable hydration

  • PN helps calm irritation and redness, supporting sensitive or stressed skin.

  • Over time, improvements are seen in:

    • Texture

    • Elasticity

    • Clarity

    • Skin tone
      The result is naturally rejuvenated, elegant and understated.

    • Under-eyes: softens crepiness, brightens and refines fine lines

    • Full face: enhances hydration, firmness and radiance

    • Under-eye area

    • Full face

    • Neck

    • Décolletage

    • Hands

FAQs

    • Deep regeneration and restoration of skin structure

    • Improved hydration and suppleness

    • Softer fine lines and enhanced elasticity

    • Clearer, more radiant tone

    • Strengthened resilience in delicate or crepey skin

    • Noticeable improvement in under-eye texture and brightness

    • Naturally refreshed, elegant finish

  • PN may appeal to individuals who:

    • Experience crepiness, dullness or early ageing

    • Struggle with delicate or fragile under-eye skin

    • Want refined rejuvenation without volume

    • Prefer biologically aligned regenerative treatments

    • Seek a naturally radiant, polished complexion

    • Desire improvement in the face, neck, décolletage or hands

    • Very well tolerated

    • Mild redness or small bumps may occur

    • Typically settle within 12–48 hours

    • Most clients resume normal activities shortly after

    • Initial course: 2–3 treatments spaced 2–4 weeks apart

    • Maintenance: every 6–9 months

    • Avoid makeup for 12 hours

    • Avoid heat, vigorous exercise and saunas for 24 hours

    • Use gentle skincare for the first day

    • SPF 30–50 daily is recommended

  • 30 minutes
    Includes consultation.